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Invitrogen
NRGN Monoclonal Antibody (C1)
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FIGURE: 1 / 5
NRGN Antibody (MA5-50991) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NRGN in human cerebrum tissue using NRGN Monoclonal Antibody (C1) (Product # MA5-50991) (30 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Mouse IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-50991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C1
Immunogen
Recombinant Human NRGN protein, Met1-Ala67 (Accession #Q92686)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calmodulin-binding protein; neurogranin (protein kinase C substrate, RC3); ng; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; RC3; unnamed protein product
Gene Aliases: 0710001B06Rik; BICKS; hng; NG; NG/RC3; Pss1; RC3
UniProt ID: (Human) Q92686, (Mouse) P60761, (Rat) Q04940
Entrez Gene ID: (Human) 4900, (Pig) 100738830, (Mouse) 64011, (Rat) 64356
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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