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Invitrogen
ProANP Monoclonal Antibody (C6)
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FIGURE: 1 / 1
ProANP Antibody (MA5-51085) in WB
Western blot analysis of ProANP in Rat Heart lysate. Samples were incubated with ProANP monoclonal antibody (Product # MA5-51085) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG secondary antibody at a dilution of 0.2 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-51085
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
C6
Immunogen
Recombinant Human NT-ProANP protein, Ala25-Arg123 (Accession #P01160)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANPRC; atrial natriuretic factor; atrial natriuretic factor prohormone; atrial natriuretic peptide prohormone; Atrial natriuretic peptide receptor 3; atriopeptigen; atriopeptin; cardiodilatin; cardiodilatin-related peptide; cardionatrin; natriuretic peptide precursor A; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor type A; NPR3; preproANF; preproANP; preprocardiodilatin-atrial natriuretic factor; preproCDD-ANF; prepronatiodilatin (PND); prepronatriodilatin; proANF; proANP; unnamed protein product
Gene Aliases: ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; PND; RATANF
UniProt ID: (Human) P01160, (Rat) P01161
Entrez Gene ID: (Human) 4878, (Rat) 24602
response to hypoxia
system process
negative regulation of systemic arterial blood pressure
cardiac conduction system development
aortic valve morphogenesis
cGMP biosynthetic process
protein folding
receptor guanylyl cyclase signaling pathway
neuropeptide signaling pathway
female pregnancy
regulation of blood pressure
positive regulation of heart rate
negative regulation of cell growth
response to insulin
response to muscle stretch
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of JUN kinase activity
negative regulation of blood pressure
cGMP metabolic process
regulation of atrial cardiac muscle cell membrane repolarization
positive regulation of cardiac muscle contraction
cell growth involved in cardiac muscle cell development
cellular response to hydrogen peroxide
cellular response to mechanical stimulus
cellular response to glucose stimulus
negative regulation of canonical Wnt signaling pathway
synaptic signaling via neuropeptide
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
positive regulation of potassium ion export across plasma membrane
negative regulation of collecting lymphatic vessel constriction
cellular response to angiotensin
response to 3-methylcholanthrene
heart development
cardiac muscle hypertrophy in response to stress
sodium ion export from cell
regulation of body fluid levels
multicellular organismal water homeostasis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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