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Invitrogen
TCEB2 Recombinant Rabbit Monoclonal Antibody (23GB5610)
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FIGURE: 1 / 4
TCEB2 Antibody (MA5-53912) in ICC/IF
Immunocytochemistry analysis of TCEB2 in HepG2 cells. Sample was incubated with TCEB2 monoclonal (Product # MA5-53912) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Low. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-53912
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5610
Immunogen
A synthesized peptide derived from human TCEB2 (80-118AA).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 18 kDa, elongin B; elongin 18 kDa subunit; elongin, 18-kD subunit; epididymis secretory sperm binding protein; RNA polymerase II transcription factor SIII p18 subunit; RNA polymerase II transcription factor SIII subunit B; SIII p18; TCEB 2; transcription elongation factor B (SIII) polypeptide 2 (18kD, elongin B); transcription elongation factor B (SIII), polypeptide 2; transcription elongation factor B (SIII), polypeptide 2 (18 kDa, elongin B); transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); transcription elongation factor B polypeptide 2; transcription elongation factor B subunit 2; unnamed protein product
Gene Aliases: 0610040H15Rik; SIII; TCEB2
UniProt ID: (Human) Q15370, (Mouse) P62869, (Rat) P62870
Entrez Gene ID: (Human) 6923, (Mouse) 67673, (Rat) 81807
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein ubiquitination
positive regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
target-directed miRNA degradation
negative regulation of transcription from RNA polymerase II promoter
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein-containing complex assembly
ribosome-associated ubiquitin-dependent protein catabolic process
negative regulation of DNA-dependent DNA replication
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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