Search
Invitrogen
CXCL12 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1273)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-54548
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Alpaca
/ VHH
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SAA1273
Immunogen
Recombinant Human CXCL12/SDF-1.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Metal-chelate chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
Compatible with Direct ELISA
Target Information
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AI174028; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine; chemokine (C-X-C motif) ligand 12; CXC; CXC motif chemokine; CXCL; CXCL12; hIRH; hSDF-1; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor; SDF-1 delta; chemokine (C-X-C motif) ligand 12 transcript variant 5; SDF-1 epsilon; chemokine (C-X-C motif) ligand 12 transcript variant 6; SDF-1 gamma; chemokine (C-X-C motif) ligand 12 transcript variant 4; SDF-1 theta; chemokine (C-X-C motif) ligand 12 transcript variant 7; SDF-1a; SDF-1b; SDF1a; stromal cell-derived factor-1 alpha; TLSF-a; TLSF-b; Tlsfa; Tlsfb; unnamed protein product
Gene Aliases: IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
UniProt ID: (Human) P48061
Entrez Gene ID: (Human) 6387
response to hypoxia
neuron migration
positive regulation of endothelial cell proliferation
cellular calcium ion homeostasis
chemotaxis
defense response
immune response
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
axon guidance
blood circulation
regulation of actin polymerization or depolymerization
positive regulation of cell proliferation
adult locomotory behavior
response to mechanical stimulus
response to virus
T cell chemotaxis
telencephalon cell migration
positive regulation of cell migration
organ regeneration
killing of cells of other organism
positive regulation of dopamine secretion
integrin activation
chemokine (C-X-C motif) ligand 12 signaling pathway
CXCL12-activated CXCR4 signaling pathway
response to peptide hormone
positive regulation of neuron differentiation
positive regulation of cell adhesion
positive regulation of axon extension involved in axon guidance
positive regulation of chemotaxis
induction of positive chemotaxis
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
regulation of calcium ion transport
cell chemotaxis
antimicrobial humoral immune response mediated by antimicrobial peptide
chemokine-mediated signaling pathway
positive regulation of monocyte chemotaxis
positive regulation of calcium ion import
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of leukocyte tethering or rolling
positive regulation of vasculature development
response to ultrasound
cellular response to chemokine
positive regulation of T cell migration
negative regulation of dendritic cell apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support