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Invitrogen
CD49e (Integrin alpha 5) Recombinant Rabbit Monoclonal Antibody (0S9S6)
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FIGURE: 1 / 2
CD49e (Integrin alpha 5) Antibody (MA5-55213) in WB
Western blot analysis of lysates from wild type (WT) and Integrin alpha 5 (ITGA5/CD49e) knockdown (KD) HeLa cells, using CD49e (Integrin alpha 5) Recombinant Monoclonal Antibody (Product # MA5-55213) at 1:1,000 dilution followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-55213
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
0S9S6
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.1 mg/mL
Amount
110 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
Product Specific Information
Immunogen Sequence: FNLDAEAPAV LSGPPGSFFG FSVEFYRPGT DGVSVLVGAP KANTSQPGVL QGGAVYLCPW GASPTQCTPI EFDSKGSRLL ESSLSSSEGE EPVEYKSLQW FGATVRAHGS SILACAPLYS WRTEKEPLSD PVGTCYLSTD NFTRILEYAP CRSDFSWAAG QGYCQGGFSA EFTKTGRVVL GGPGSYFWQG QILSATQEQI AESYYPEYLI NLVQGQLQTR QASSIYDDSY LGYSVAVGEF SGDDTEDFVA GVPKGNLTYG YVTILNGSDI RSLYNFSGEQ MASYFGYAVA ATDVNGDGLD DLLVGAPLLM DRTPDGRPQE VGRVYVYLQH PAGIEPTPTL TLTGHDEFGR FGSSLTPLGD LDQDGYNDVA IGAPFGGETQ QGVVFVFPGG PGGLGSKPSQ VLQPLWAASH TPDFFGSALR GGRDLDGNGY PDLIVGSFGV DKAVVYRGRP IVSASASLTI FPAMFNPEER SCSLEGNPVA CINLSFCLNA SGKHVADSIG FTVELQLDWQ KQKGGVRRAL FLASRQATLT QTLLIQNGAR EDCREMKIYL RNESEFRDKL SPIHIALNFS LDPQAPVDSH GLRPALHYQS KSRIEDKAQI LLDCGEDNIC VPDLQLEVFG EQNHVYLGDK NALNLTFHAQ NVGEGGAYEA ELRVTAPPEA EYSGLVRHPG NFSSLSCDYF AVNQSRLLVC DLGNPMKAGA SLWGGLRFTV PHLRDTKKTI QFDFQILSKN LNNSQSDVVS FRLSVEAQAQ VTLNGVSKPE AVLFPVSDWH PRDQPQKEED LGPAVHHVYE LINQGPSSIS QGVLELSCPQ ALEGQQLLYV TRVTGLNCTT NHPINPKGLE LDPEGSLHHQ QKREAPSRSS ASSGPQILKC PEAECFRLRC ELGPLHQQES QSLQLHFRVW AKTFLQREHQ PFSLQCEAVY KALKMPYRIL PRQLPQKERQ VATAVQWTKA EGSY
Target Information
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; surface glycoprotein receptor; unnamed protein product; very late activation protein 5, alpha subunit
Gene Aliases: CD49e; FNRA; VLA-5; VLA5A
UniProt ID: (Human) P08648
Entrez Gene ID: (Human) 3678
angiogenesis
formation of primary germ layer
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
female pregnancy
tissue development
positive regulation of cell-substrate adhesion
response to muscle activity
CD40 signaling pathway
positive regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
cell adhesion mediated by integrin
heterotypic cell-cell adhesion
wound healing, spreading of epidermal cells
endodermal cell differentiation
regulation of angiogenesis
cell-cell adhesion
positive regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
negative regulation of anoikis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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