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Invitrogen
ITPA Recombinant Rabbit Monoclonal Antibody (2O6K5)
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FIGURE: 1 / 1
ITPA Antibody (MA5-55475) in WB
Western Blot analysis of various lysates using ITPA Recombinant Monoclonal Antibody (Product # MA5-55475) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-55475
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2O6K5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human ITPA.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.5 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
Product Specific Information
Immunogen Sequence: VEDTCLCFNA LGGLPGPYIK WFLEKLKPEG LHQLLAGFED KSAYALCTFA LSTGDPSQPV RLFRGRTSGR IVAPRGCQDF G
Target Information
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); inosine triphosphatase (nucleoside triphosphate pyrophosphatase) isoform ITPA_1; inosine triphosphatase (nucleoside triphosphate pyrophosphatase) isoform ITPA_2; inosine triphosphate pyrophosphohydrolase; My049 protein; non-canonical purine NTP pyrophosphatase; non-standard purine NTP pyrophosphatase; nucleoside triphosphate pyrophosphatase; nucleoside-triphosphate diphosphatase; putative oncogene protein HLC14-06-P; unnamed protein product; XTP/dITP diphosphatase
Gene Aliases: 2010016I08Rik; C20orf37; DEE35; dJ794I6.3; HLC14-06-P; Itp; ITPase; My049; NTPase
UniProt ID: (Human) Q9BY32, (Mouse) Q9D892
Entrez Gene ID: (Human) 3704, (Mouse) 16434
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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