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Invitrogen
NPR3 Recombinant Rabbit Monoclonal Antibody (24GB3585)
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FIGURE: 1 / 3
NPR3 Antibody (MA5-57097) in ICC/IF
Immunocytochemical staining of NPR3 in C2C12 cells using NPR3 Recombinant Monoclonal Antibody (Product # MA5-57097) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Natriuretic peptide receptor 3 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57097
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB3585
Immunogen
A synthesized peptide derived from human Natriuretic Peptide Receptor C (aa 500-541)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.2 mg/mL
Amount
120 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A NPR-C; amino acid feature: cytoplasmic domain, bp 1509 .. 1622; amino acid feature: extracellular domain, bp 138 .. 1442; amino acid feature: transmembrane domain, bp 1443 .. 1508; ANP-C; ANPR-C; ANPRC; atrial natriuretic peptide C-type receptor; atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide clearence receptor 3; atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; longjohn; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); Nppc receptor; NPR-C; strigosus; unnamed protein product
Gene Aliases: ANP-C; ANP-CR; ANPR-C; ANPRC; BOMOS; C5orf23; EF-2; GUCY2B; lgj; NPR-C; NPRC; stri
UniProt ID: (Human) P17342, (Mouse) P70180, (Rat) P41740
Entrez Gene ID: (Human) 4883, (Mouse) 18162, (Rat) 25339
skeletal system development
osteoclast proliferation
signal transduction
G-protein coupled receptor signaling pathway
regulation of blood pressure
regulation of osteoblast proliferation
positive regulation of urine volume
negative regulation of cold-induced thermogenesis
positive regulation of relaxation of smooth muscle
angiogenesis
blood vessel remodeling
response to ischemia
cGMP biosynthetic process
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
vasodilation
negative regulation of smooth muscle cell proliferation
positive regulation of pancreatic juice secretion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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