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Invitrogen
NDUFS2 Recombinant Rabbit Monoclonal Antibody (24GB495)
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FIGURE: 1 / 2
NDUFS2 Antibody (MA5-57108) in ICC/IF
Immunocytochemical staining of NDUFS2 in C2C12 cells using NDUFS2 Recombinant Monoclonal Antibody (Product # MA5-57107) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; NDUFS2 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57108
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB495
Immunogen
A synthesized peptide derived from human NDUFS2 (aa 300-434)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.8 mg/mL
Amount
16 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-49kD; comp; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; complex I iron sulphur protein subunit; 49kDa subunit; complex I-49kD; NADH dehydrogenase (ubiquinone) Fe-S protein 2; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit; unnamed protein product
Gene Aliases: CI-49; CI-49kD; LHONAR2; MC1DN6
UniProt ID: (Human) O75306, (Rat) Q641Y2, (Mouse) Q91WD5
Entrez Gene ID: (Human) 4720, (Rat) 289218, (Mouse) 226646
mitochondrial electron transport, NADH to ubiquinone
biological_process
neurogenesis
mitochondrial respiratory chain complex I assembly
gliogenesis
mitochondrial ATP synthesis coupled electron transport
neural precursor cell proliferation
cellular response to oxygen levels
hydrogen ion transmembrane transport
aerobic respiration
mitochondrial ATP synthesis coupled proton transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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