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Invitrogen
POLD1 Recombinant Rabbit Monoclonal Antibody (24GB4155)
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FIGURE: 1 / 3
POLD1 Antibody (MA5-57177) in ICC/IF
Immunocytochemical staining of POLD1 in HepG2 cells using POLD1 Recombinant Monoclonal Antibody (Product # MA5-57177) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; POLD1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57177
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB4155
Immunogen
A synthesized peptide derived from human POLD1 (aa 1000-1065)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.5 mg/mL
Amount
150 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exodeoxyribonuclease; CDC2 homolog; DAN polymerase delta 1, catalytic subunit; DNA polymerase delta 1, catalytic domain; DNA polymerase delta, catalytic subunit; DNA polymerase subunit delta p125; DNA-directed DNA polymerase delta 1; POL D; POLD1; polymerase (DNA directed), delta 1, catalytic subunit; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D; unnamed protein product
Gene Aliases: 125kDa; CDC2; CRCS10; IMD120; MDPL; POLD
UniProt ID: (Human) P28340, (Rat) O54747, (Mouse) P52431
Entrez Gene ID: (Human) 5424, (Rat) 59294, (Mouse) 18971
DNA synthesis involved in DNA repair
DNA replication
DNA-dependent DNA replication
base-excision repair, gap-filling
nucleotide-excision repair, DNA gap filling
DNA replication proofreading
fatty acid homeostasis
error-free translesion synthesis
DNA biosynthetic process
DNA repair
response to UV
cellular response to UV
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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