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Invitrogen
TUB Recombinant Rabbit Monoclonal Antibody (24GB1795)
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FIGURE: 1 / 3
TUB Antibody (MA5-57297) in ICC/IF
Immunocytochemical staining of TUB in HT-1080 cells using TUB Recombinant Monoclonal Antibody (Product # MA5-57297) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; TUB1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1795
Immunogen
A synthesized peptide derived from human TUB1 (aa 1-50)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: candidate tub gene; similar to brain putative tub gene product, GenBank Accession Number U52433; similar to CAEEL48.2K protein, Swiss-Prot Accession Number Q09306; similar to mouse p46 protein. Swiss-Prot Accession Number P46686; first ATG in open reading ; candidate tub gene; similar to C.elegans 48.2 protein Swiss-Prot Accession Number Q09306; similar to mouse p46 protein Swiss-Prot Accession Number P46686; retinal degeneration 5; tubby bipartite transcription factor; tubby candidate; tubby homolog; tubby homologue; unnamed protein product
Gene Aliases: rd5; RDOB; tub
UniProt ID: (Human) P50607, (Mouse) P50586, (Rat) O88808
Entrez Gene ID: (Human) 7275, (Mouse) 22141, (Rat) 25609
phagocytosis, recognition
sensory perception of sound
regulation of G-protein coupled receptor protein signaling pathway
intraciliary transport
camera-type eye development
photoreceptor cell maintenance
positive regulation of phagocytosis
retina development in camera-type eye
protein localization to cilium
receptor localization to nonmotile primary cilium
protein localization to photoreceptor outer segment
response to hormone
response to cocaine
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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