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Invitrogen
NuMA Recombinant Rabbit Monoclonal Antibody (24GB1290)
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FIGURE: 1 / 4
NuMA Antibody (MA5-57526) in ICC/IF
Immunocytochemistry analysis of NuMA in HepG2 cells. Sample was incubated with NuMA monoclonal (Product # MA5-57526) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: High. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1290
Immunogen
A synthesized peptide derived from human NUMA1 (aa 2000-2100)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
NuMA (nuclear mitotic apparatus) is a long coil-coiled protein that plays a role in the interphase and mitosis phases of a cell cycle. In interphase, it has been hypothesized to play a structural role in the nucleoskeleton that may be important in nuclear organization and functions. During mitosis, it is associated with spindle microtubule organization and chromosome positioning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centrophilin stabilizes mitotic spindle in mitotic cells; nuclear matrix protein-22; SP-H antigen; structural nuclear protein; unnamed protein product
Gene Aliases: 6720401E04Rik; NMP-22; NUMA
UniProt ID: (Human) Q14980, (Mouse) E9Q7G0
Entrez Gene ID: (Human) 4926, (Rat) 308870, (Mouse) 101706
establishment of mitotic spindle orientation
microtubule bundle formation
nucleus organization
positive regulation of BMP signaling pathway
astral microtubule organization
positive regulation of microtubule polymerization
positive regulation of intracellular transport
positive regulation of keratinocyte differentiation
meiotic cell cycle
positive regulation of hair follicle development
positive regulation of chromosome segregation
anastral spindle assembly
regulation of mitotic spindle organization
regulation of metaphase plate congression
positive regulation of protein localization to spindle pole body
positive regulation of mitotic spindle elongation
positive regulation of protein localization to cell cortex
positive regulation of chromosome separation
positive regulation of spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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