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Invitrogen
Plexin-A1 Recombinant Rabbit Monoclonal Antibody (24GB1245)
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FIGURE: 1 / 3
Plexin-A1 Antibody (MA5-57608) in WB
Western blot analysis of Plexin-A1. Total cell lysates (30 μg) from C2C12, H9c2, HAP-1, HeLa, HepG2, and HT-1080 cell lines were loaded and separated by SDS-PAGE. The blot was incubated with Plexin-A1 Recombinant Monoclonal Antibody (Product # MA5-57608) at a 1:5,000 dilution and HRP-conjugated goat anti-rabbit secondary antibody at a 1:20,000 dilution respectively.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57608
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1245
Immunogen
A synthesized peptide derived from human Plexin A1 (aa 100-180)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.7 mg/mL
Amount
70 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plex 1; plexin 1; plexin-1; semaphorin receptor NOV; unnamed protein product
Gene Aliases: 2600013D04Rik; DWOPNED; mKIAA4053; NOV; NOVP; PlexA1; PLEXIN-A1; PLXN1; RGD1560871
UniProt ID: (Human) Q9UIW2, (Mouse) P70206
Entrez Gene ID: (Human) 5361, (Rat) 362398, (Mouse) 18844
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
synapse assembly
regulation of smooth muscle cell migration
cranial nerve morphogenesis
olfactory nerve formation
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
central nervous system neuron development
regulation of cell migration
forebrain development
regulation of locomotion
epithelium development
dichotomous subdivision of terminal units involved in salivary gland branching
semaphorin-plexin signaling pathway
neuron projection guidance
regulation of plasma membrane bounded cell projection organization
neuron projection extension
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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