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RAB3C Recombinant Rabbit Monoclonal Antibody (10X10S0)
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FIGURE: 1 / 2
RAB3C Antibody (MA5-57988) in WB
Western blot analysis of RAB3C in mouse brain and rat testis (25 µg/lane). Samples were incubated overnight at 4°C with RAB3C Recombinant Monoclonal Antibody (Product # MA5-57988) using a dilution of 1:2, 000. Followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) Secondary Antibody at 1:10,000 dilution. Blocking buffer: 3% nonfat dry milk in TBST; Exposure: 60 seconds.
Product Details
MA5-57988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
10X10S0
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
1.18 mg/mL
Amount
118 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
Immunogen sequence: IKTYSWDNAQ VILVGNKCDM EDERVISTER GQHLGEQLGF EFFETSAKDN INVKQTFERL VDIICDKMSE SLETDPAITA AKQNTRLKET PPPPQPNCAC
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ras-related protein Rab-3C; small GTP-binding protein Rab3C
Gene Aliases: 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; AI850886; RAB3C
UniProt ID: (Human) Q96E17, (Rat) P62824, (Mouse) P62823
Entrez Gene ID: (Human) 115827, (Rat) 171058, (Mouse) 67295
exocytosis
protein transport
regulation of exocytosis
antigen processing and presentation
intracellular protein transport
vesicle docking involved in exocytosis
metabolic process
protein secretion
synaptic vesicle exocytosis
Rab protein signal transduction
protein localization to plasma membrane
transport
small GTPase mediated signal transduction
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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