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Invitrogen
BAFF Recombinant Rabbit Monoclonal Antibody (2P6I3)
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FIGURE: 1 / 2
BAFF Antibody (MA5-58151) in IHC (P)
Immunohistochemistry analysis of BAFF with paraffin-embedded Mouse lung tissue. The tissue was incubated with BAFF Recombinant Monoclonal Antibody (Product # MA5-58152) using a 1:200 dilution (40x lens). Followed by Cy3-conjugated Goat anti-Rabbit IgG (H+L) Secondary Antibody (Red) using a 1:500 dilution. DAPI was used for nuclear staining (Blue). High pressure antigen retrieval performed with 0.01M Citrate... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-58151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2P6I3
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.26 mg/mL
Amount
25.2 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
Immunogen sequence: AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
Target Information
BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: b cell-activating factor; BAFF; TNF family; BAFF; TNFalpha homolog; TNF family member; tumor necrosis factor ligand 7a; unnamed protein product
Gene Aliases: BAFF; BLyS; D8Ertd387e; TALL-1; TALL1; THANK; TNFSF20; Tnlg7a; zTNF4
UniProt ID: (Mouse) Q9WU72
Entrez Gene ID: (Mouse) 24099
B cell homeostasis
lymphocyte homeostasis
transitional one stage B cell differentiation
positive regulation of germinal center formation
immune response
gene expression
B cell differentiation
positive regulation of B cell proliferation
T cell costimulation
B cell costimulation
tumor necrosis factor-mediated signaling pathway
positive regulation of T cell proliferation
B cell activation
skin development
regulation of immune response
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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