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CD203c Recombinant Rabbit Monoclonal Antibody (8F10L7)
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FIGURE: 1 / 1
CD203c Antibody (MA5-58179) in ICC/IF
Immunocytochemistry analysis of CD203c using 293F cells. The cells were incubated using 1:200 dilution with CD203c Recombinant Monoclonal Antibody (Product # MA5-58180) (100x lens). Followed by further incubation with Cy3-conjugated Goat anti-Rabbit IgG (H+L) using a 1:500 dilution (Red). DAPI was used for nuclear staining (Blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-58179
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
8F10L7
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.05 mg/mL
Amount
21 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
Immunogen sequence: SHAEEVSKFS VCGFANPLPT ESLDCFCPHL QNSTQLEQVN QMLNLTQEEI TATVKVNLPF GRPRVLQKNV DHCLLYHREY VSGFGKAMRM PMWSSYTVPQ LGDTSPLPPT VPDCLRADVR VPPSESQKCS FYLADKNITH GFLYPPASNR TSDSQYDALI TSNLVPMYEE FRKMWDYFHS VLLIKHATER NGVNVVSGPI FDYNYDGHFD APDEITKHLA NTDVPIPTHY FVVLTSCKNK SHTPENCPGW LDVLPFIIPH RPTNVESCPE GKPEALWVEE RFTAHIARVR DVELLTGLDF YQDKVQPVSE ILQLKTYLPT FETTI
Target Information
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alkaline phosphodiesterase I; dinucleoside polyphosphatase; dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); ENPP3; gp130RB13-6; NPPase; nucleotide diphosphatase; nucleotide pyrophosphatase; phosphodiesterase I/nucleotide pyrophosphatase 3; phosphodiesterase-I beta; unnamed protein product
Gene Aliases: B10; CD203c; NPP3; PD-IBETA; PDNP3
UniProt ID: (Human) O14638
Entrez Gene ID: (Human) 5169
nucleic acid binding
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
phosphodiesterase I activity
calcium ion binding
5'-nucleotidase activity
zinc ion binding
pyrophosphatase activity
hydrolase activity
bis(5'-adenosyl)-pentaphosphatase activity
GTP diphosphatase activity
UTP diphosphatase activity
metal ion binding
nucleoside-triphosphate diphosphatase activity
ATP diphosphatase activity
bis(5'-adenosyl)-triphosphatase activity
cyclic-GMP-AMP hydrolase activity
basophil activation involved in immune response
pyrimidine nucleotide metabolic process
phosphate-containing compound metabolic process
nucleoside triphosphate catabolic process
inorganic diphosphate transport
negative regulation of mast cell activation involved in immune response
ATP metabolic process
negative regulation of inflammatory response
phosphate ion homeostasis
negative regulation of mast cell proliferation
negative regulation of cGAS/STING signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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