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Invitrogen
Myostatin (Trevogrumab Biosimilar) Recombinant Human Monoclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-58723
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4SP
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H-Myo-Propeptide; H-Myostatin; myostatin-b; transforming growth factor-beta superfamily member; unnamed protein product
Gene Aliases: GDF8; MSLHP
UniProt ID: (Human) O14793
Entrez Gene ID: (Human) 2660
transforming growth factor beta receptor signaling pathway
muscle organ development
skeletal muscle tissue development
response to gravity
positive regulation of lamellipodium assembly
positive regulation of macrophage chemotaxis
skeletal muscle atrophy
negative regulation of muscle hypertrophy
skeletal muscle satellite cell differentiation
myoblast migration involved in skeletal muscle regeneration
response to muscle activity
ovulation cycle process
response to testosterone
skeletal muscle tissue regeneration
response to estrogen
response to ethanol
negative regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
negative regulation of insulin receptor signaling pathway
muscle cell cellular homeostasis
negative regulation of skeletal muscle tissue growth
response to glucocorticoid
response to electrical stimulus
negative regulation of protein kinase B signaling
trophoblast cell migration
cellular response to hypoxia
negative regulation of skeletal muscle satellite cell proliferation
negative regulation of satellite cell differentiation
negative regulation of myoblast proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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