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Invitrogen
CGRPR (Erenumab Biosimilar) Recombinant Human Monoclonal Antibody
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Product Details
MA5-58829
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG2SA, lambda
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
The Calcitonin Gene-Related Peptide Receptor (CGRPR) primarily refers to the receptor complex involving the gene CALCRL (calcitonin receptor-like receptor) and the receptor activity-modifying protein (RAMP1). This complex is vital in the transmission of signals for the peptide hormone calcitonin gene-related peptide (CGRP). CALCRL is located on chromosome 2 and is part of the G protein-coupled receptor family. The functional receptor is significant in mediating vascular smooth muscle cell relaxation and is thus involved in various physiological responses, including vasodilation, pain transmission, and neurogenic inflammation. The receptor’s activation by CGRP plays an essential role in migraine pathophysiology by promoting vasodilation and influencing pain signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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