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Cannabinoid Receptor 1 (Nimacimab Biosimilar) Recombinant Human Monoclonal Antibody
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FIGURE: 1 / 3
Cannabinoid Receptor 1 (Nimacimab Biosimilar) Antibody (MA5-59147) in Flow
Flow cytometry analysis of Cannabinoid Receptor 1 (Nimacimab Biosimilar) Recombinant monoclonal antibody (Product # MA5-59147). Human CB1/CNR1 EGFP HEK293 Cell Line were stained with (nimacimab) and negative control protein respectively, washed and then followed by APC and analyzed with FACS, EC50=0.028 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-59147
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4SP, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL once reconstituted
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cannabinoid receptor 1 (brain); CB1 receptor; central cannabinoid receptor; HGNC:2159; N-terminal variant; OTTHUMP00000016839; RP1-23D17.1; unnamed protein product
Gene Aliases: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
UniProt ID: (Human) P21554
Entrez Gene ID: (Human) 1268
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cannabinoid signaling pathway
retrograde trans-synaptic signaling by endocannabinoid
regulation of presynaptic cytosolic calcium ion concentration
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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