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Invitrogen

ITGA5/ITGB1 (Volociximab Biosimilar) Recombinant Human Monoclonal Antibody

View all (10) ITGA5/ITGB1 antibodies

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Product Details

MA5-59893

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-

Functional Assay (Functional)

Assay-dependent
-

Surface plasmon resonance (SPR)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG4SP

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Dry ice (international)

RRID

AB_3682912

Product Specific Information

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.

MA5-59893 is a human/mouse chimeric antibody. The variable regions from one species have been grafted to the backbone of the other species.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; glycoprotein IIa; integrin alpha-F; integrin beta 1; integrin beta-1 subunit (cytoplasmic domain); Integrin beta1; integrin VLA-4 beta subunit; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITGA5/SLC9B1 fusion; surface glycoprotein receptor; unnamed protein product; very late activation protein 5, alpha subunit; very late activation protein, beta polypeptide

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Gene Aliases: CD29; CD49e; FNRA; FNRB; GPIIA; MDF2; MSK12; VLA-5; VLA-BETA; VLA5A; VLAB

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UniProt ID: (Human) P08648, (Human) P05556

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Entrez Gene ID: (Human) 3678, (Human) 3688

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Function(s)
receptor binding epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding calcium ion binding protein binding signaling receptor activity vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding magnesium ion binding fibronectin binding protease binding actin binding obsolete cell adhesion receptor activity coreceptor activity protein kinase binding C-X3-C chemokine binding laminin binding macromolecular complex binding cadherin binding protein heterodimerization activity collagen binding involved in cell-matrix adhesion integrin binding involved in cell-matrix adhesion protein tyrosine kinase binding
Process(es)
angiogenesis formation of primary germ layer cell adhesion cell-matrix adhesion integrin-mediated signaling pathway female pregnancy tissue development positive regulation of cell-substrate adhesion response to muscle activity CD40 signaling pathway positive regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion cell adhesion mediated by integrin heterotypic cell-cell adhesion wound healing, spreading of epidermal cells endodermal cell differentiation regulation of angiogenesis cell-cell adhesion positive regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis negative regulation of anoikis establishment of mitotic spindle orientation phagocytosis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway myoblast fusion regulation of collagen catabolic process positive regulation of fibroblast migration cell migration cell projection organization lamellipodium assembly B cell differentiation extracellular matrix organization receptor internalization cell-cell adhesion mediated by integrin maintenance of blood-brain barrier positive regulation of apoptotic process stress fiber assembly positive regulation of GTPase activity myoblast differentiation positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis negative regulation of vasoconstriction mesodermal cell differentiation regulation of developmental process modulation of synaptic transmission leukocyte tethering or rolling positive regulation of protein kinase B signaling positive regulation of glutamate uptake involved in transmission of nerve impulse cellular response to low-density lipoprotein particle stimulus basement membrane organization positive regulation of wound healing regulation of spontaneous synaptic transmission reactive gliosis positive regulation of protein localization to plasma membrane regulation of synapse pruning
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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