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Invitrogen
ADORA2A (Biosimilar) Recombinant Human Monoclonal Antibody
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FIGURE: 1 / 4
ADORA2A (Biosimilar) Antibody (MA5-59939) in Flow
Flow cytometry analysis of ADORA2A (Biosimilar) Recombinant monoclonal antibody (Product # MA5-59939). Cynomolgus/Rhesus Macaque A2AR HEK293 Cell Line were stained with (3F6-9G5) and negative control protein respectively, washed and then followed by PE and analyzed with FACS. The EC50 was approximately 0.215 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-59939
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL once reconstituted
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term 3F6-9G5.
Target Information
ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A2a receptor; adenosine receptor subtype A2a; ADORA2A; AR; hA2aR; unnamed protein product
Gene Aliases: A2aR; ADORA2; RDC8
UniProt ID: (Human) P29274
Entrez Gene ID: (Human) 135
synaptic transmission, dopaminergic
adenosine receptor signaling pathway
regulation of transcription, DNA-templated
phagocytosis
apoptotic process
inflammatory response
cellular defense response
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
cell-cell signaling
synaptic transmission, cholinergic
central nervous system development
blood coagulation
sensory perception
locomotory behavior
blood circulation
negative regulation of cell proliferation
response to xenobiotic stimulus
positive regulation of glutamate secretion
positive regulation of acetylcholine secretion, neurotransmission
regulation of norepinephrine secretion
response to purine-containing compound
response to caffeine
synaptic transmission, glutamatergic
positive regulation of urine volume
vasodilation
eating behavior
negative regulation of vascular permeability
response to alkaloid
negative regulation of neuron apoptotic process
positive regulation of circadian sleep/wake cycle, sleep
astrocyte activation
neuron projection morphogenesis
positive regulation of protein secretion
regulation of mitochondrial membrane potential
membrane depolarization
regulation of calcium ion transport
positive regulation of synaptic transmission, glutamatergic
excitatory postsynaptic potential
prepulse inhibition
positive regulation of ERK1 and ERK2 cascade
presynaptic modulation of chemical synaptic transmission
positive regulation of long-term synaptic potentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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