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Invitrogen
Influenza A H1N1 HA (Swine Flu 2009) Recombinant Rabbit Monoclonal Antibody (376)
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Product Details
MA5-60306
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
376
Immunogen
Recombinant H1N1 HA protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.0, with 10% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recognizes H1N1 (A/California/04/2009) HA; H1N1 (A/California/07/2009) HA. Has cross-reactivity in ELISA with: H1N1 (A/Solomon Islands/3/2006) HA; H1N1 (A/Ohio/UR06-0091/2007) HA; H1N1 (A/New Caledonia/20/1999) HA; H1N1 (A/Puerto Rico/8/1934) HA; H1N1 (A/WSN/1933) HA; H1N2 (A/swine/Guangxi/13/2006) HA; H1N3 (A/duck/NZL/160/1976) HA; H5N1 (A/Viet Nam/1203/2004) HA; H5N1 (A/turkey/Turkey/1/2005) HA; H5N1 (A/Anhui/1/2005) HA2 Sub-unit; No cross-reactivity in ELISA with: H1N1 (A/California/04/2009) HA1 Sub-unit; H1N1 (A/Brevig Mission/1/1918) HA; H1N1 (A/Brisbane/59/2007) HA; H5N1 (A/Indonesia/5/2005) HA; H5N1 (A/Anhui/1/2005) HA; H3N2 (A/Brisbane/10/2007) HA; H5N1 (A/bar-headed goose/Qinghai/14/2008) HA; Influenza B (B/Florida/4/2006) HA
Target Information
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: flu hemagglutinin; H1N1 HA; H1N1 hemagglutinin; Influenza H1N1; influenza hemagglutinin
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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