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Invitrogen
RBP4 Recombinant Rabbit Monoclonal Antibody (9G7)
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FIGURE: 1 / 2
RBP4 Antibody (MA5-60664) in IHC (P)
Immunohistochemistry analysis of RBP4 in paraffin-embedded human kidney tissue. Samples were incubated with RBP4 Recombinant Monoclonal antibody (Product # MA5-60664) using a dilution of 1:100 followed by detection with Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Sectio... View More
Product Details
MA5-60664
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
9G7
Immunogen
A synthesized peptide derived from human RBP4.
Conjugate
Form
Liquid
Concentration
0.225 mg/mL
Amount
22.5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial; unnamed protein product
Gene Aliases: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950
retinoid metabolic process
eye development
positive regulation of immunoglobulin production
gluconeogenesis
spermatogenesis
heart development
visual perception
phototransduction, visible light
male gonad development
response to xenobiotic stimulus
response to muscle activity
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
response to insulin
retinol transport
retinol metabolic process
retinal metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
detection of light stimulus involved in visual perception
retina development in camera-type eye
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
vitamin A import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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