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Invitrogen
KIR3DL2 Recombinant Human Monoclonal Antibody (8D10)
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FIGURE: 1 / 2
KIR3DL2 Antibody (MA5-60726) in Flow
Flow cytometry of KIR3DL2 in untransfected HEK-293T cells (green line) and transfected Human KIR3DL2 HEK-293T stable cells (red line). Samples were incubated with KIR3DL2 Recombinant Monoclonal antibody (Product # MA5-60726) followed by FITC-conjugated anti-Human IgG Fc.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-60726
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
8D10
Immunogen
Recombinant Human KIR3DL2 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD158 antigen-like family member K; killer cell immunoglobulin-like receptor 2DL2; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2; killer Ig receptor; killer-cell immunoglobulin-like receptor; KIR antigen 3DL2; KIR3DL2; LOC727787; MHC class I NK cell receptor; natural killer cell receptor; natural killer-associated transcript 4; Nkat4a; putative; NKAT4b; putative; p70 killer cell inhibitory receptor; p70 natural killer cell receptor clone CL-5; p70 NK receptor CL-5
Gene Aliases: 3DL2; CD158K; KIR-3DL2; NKAT-4; NKAT4; NKAT4B; p140
UniProt ID: (Human) P43630
Entrez Gene ID: (Human) 3812
Disclaimer
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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