Search
Invitrogen
pro-HGF Activator Monoclonal Antibody (198811)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-61030
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
198811
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Pro-HGF Activator, Gln35-Ser653 (predicted)
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
500 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Pro-HGF Activator (HGFAC) is a gene that encodes the Hepatocyte Growth Factor Activator, a serine protease involved in the activation of hepatocyte growth factor (HGF). HGF is a critical growth factor that regulates cell growth, cell motility, and morphogenesis by activating the c-Met receptor. The HGFAC protein is synthesized as an inactive zymogen, known as pro-HGF activator, which requires proteolytic cleavage to become active. Once activated, HGFAC can convert inactive pro-HGF into its active form, thereby facilitating various physiological processes such as tissue regeneration, wound healing, and organ development. Dysregulation of HGFAC activity has been associated with pathological conditions, including tumor progression and metastasis, liver fibrosis, and cardiovascular diseases. Due to its significant role in activating HGF and influencing cellular behaviors, HGFAC is an important target for research aimed at developing therapeutic strategies for diseases involving aberrant cell growth and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support