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          • Primary Antibodies ›
          • CXCL11 Antibodies

          Invitrogen

          CXCL11 Monoclonal Antibody (131327)

          View all (18) CXCL11 antibodies

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          Cite CXCL11 Monoclonal Antibody (131327)

          Additional Information:
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          • Antibody Testing Data (1)
          CXCL11 Antibody in Neutralization (Neu)
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          CXCL11 Antibody in Neutralization (Neu)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CXCL11 Antibody (MA5-61586) in Neu

          Chemotaxis Induced by CXCL11 and Neutralization by Mouse CXCL11 monoclonal antibody (Product # MA5-61586). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CXCL11 Antibody in Neutralization (Neu)
          CXCL11 Monoclonal Antibody (131327)

          Product Details

          MA5-61586

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Neutralization (Neu)

          0.4-2.0 µg/mL
          -
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Rat / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          131327

          Immunogen

          E. coli-derived recombinant mouse CXCL11/I-TAC, Phe22-Met100
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.5 mg/mL

          Amount

          500 µg

          Purification

          Protein A/G

          Storage buffer

          PBS with 5% trehalose

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3702198

          Product Specific Information

          Reconstitute at 0.5 mg/mL in sterile PBS.

          Target Information

          Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 11; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; I-TAC; Interferon-inducible T-cell alpha chemoattractant; MGC102770; small inducible cytokine subfamily B (Cys-X-Cys), member 11; Small-inducible cytokine B11

          View more View less

          Gene Aliases: b-R1; betaR1; Cxc11; Cxcl11; H174; I-tac; Ip9; Itac; Scyb11; Scyb9b

          View more View less

          UniProt ID: (Mouse) Q9JHH5

          View more View less

          Entrez Gene ID: (Mouse) 56066

          View more View less

          Function(s)
          cytokine activity chemokine activity CXCR3 chemokine receptor binding chemokine
          Process(es)
          positive regulation of leukocyte chemotaxis chemotaxis inflammatory response immune response G-protein coupled receptor signaling pathway T cell chemotaxis response to lipopolysaccharide regulation of cell proliferation cell chemotaxis chemokine-mediated signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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