Search
Invitrogen
OPRM1 Monoclonal Antibody (677014)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-61732
Product Specifications
Species Reactivity
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
677014
Immunogen
Synthetic peptide corresponding to His385-Pro398 of rat µ Opioid R/OPRM1
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: hMOP; KIAA0403; M-OR-1; MOR-1; MOR-1C; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; Mu-type opioid receptor; MUOR1; Opioid mu receptor; Opioid Receptor; Opioid receptor B; OTTHUMP00000017463
Gene Aliases: MORA; Oprm; Oprm1; Oprrm1; Ror-b
UniProt ID: (Rat) P33535
Entrez Gene ID: (Rat) 25601
G-protein alpha-subunit binding
G-protein coupled receptor activity
beta-endorphin receptor activity
opioid receptor activity
voltage-gated calcium channel activity
protein binding
protein domain specific binding
filamin binding
G-protein beta-subunit binding
morphine receptor activity
neuropeptide binding
G-protein coupled receptor
transmembrane signal receptor
acute inflammatory response to antigenic stimulus
immune response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
locomotory behavior
sensory perception of pain
adenylate cyclase-inhibiting opioid receptor signaling pathway
response to food
positive regulation of appetite
response to lipopolysaccharide
opioid receptor signaling pathway
wound healing
response to cocaine
response to morphine
positive regulation of cAMP-mediated signaling
negative regulation of cAMP-mediated signaling
negative regulation of nitric oxide biosynthetic process
positive regulation of nitric oxide biosynthetic process
response to ethanol
behavioral response to ethanol
positive regulation of neurogenesis
negative regulation of cytosolic calcium ion concentration
regulation of sensory perception of pain
excitatory postsynaptic potential
negative regulation of Wnt protein secretion
positive regulation of ERK1 and ERK2 cascade
calcium ion transmembrane transport
response to growth factor
cellular response to morphine
regulation of N-methyl-D-aspartate selective glutamate receptor activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support