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Invitrogen
MYH7 Monoclonal Antibody (940906)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-61990
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
940906
Immunogen
Human MYH7 synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta-myosin heavy chain; cardiac muscle myosin heavy chain 7 beta; myHC-beta; myhc-slow; myosin 7; myosin heavy chain; myosin heavy chain beta-subunit; myosin heavy chain MYH7; muscle filament; myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 7, cardiac muscle, beta; rhabdomyosarcoma antigen MU-RMS-40.7A; sarcomeric protein; unnamed protein product
Gene Aliases: CMD1S; CMH1; CMYO7A; CMYO7B; CMYP7A; CMYP7B; MPD1; MYHCB; SPMD; SPMM
UniProt ID: (Human) P12883
Entrez Gene ID: (Human) 4625
regulation of the force of heart contraction
regulation of heart rate
skeletal muscle contraction
muscle contraction
striated muscle contraction
adult heart development
regulation of the force of skeletal muscle contraction
muscle filament sliding
regulation of slow-twitch skeletal muscle fiber contraction
ATP metabolic process
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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