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Invitrogen
Claudin 18.2 Recombinant Rabbit Monoclonal Antibody (RM510)
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Product Details
MA562095
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
RM510
Immunogen
A peptide corresponding to residues of human CLDN18.2 (Claudin 18.2) (Isoform A2 of Claudin-18).
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Purification
Protein A
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts to human CLDN18.2 (Claudin 18.2) (Isoform A2 of Claudin-18). This antibody may also react to mouse or rat CLDN18.2, as predicted by immunogen homology.
Target Information
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: claudin 18-like; Claudin-18; SFTA5; SFTPJ; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J; unnamed protein product
Gene Aliases: CLDN18; SFTA5; SFTPJ; UNQ778/PRO1572
UniProt ID: (Human) P56856, (Mouse) P56857, (Rat) Q5I0E5
Entrez Gene ID: (Human) 51208, (Mouse) 56492, (Rat) 315953
cell adhesion
negative regulation of tumor necrosis factor-mediated signaling pathway
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
protein localization to nucleus
organ growth
epithelial fluid transport
response to ethanol
negative regulation of bone resorption
lung alveolus development
digestive tract development
epithelial cell proliferation
bicellular tight junction assembly
cellular response to estrogen stimulus
tight junction organization
negative regulation of protein localization to nucleus
negative regulation of osteoclast development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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