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Invitrogen
DLK1 Recombinant Rabbit Monoclonal Antibody (PSH04-76)
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FIGURE: 1 / 12
DLK1 Antibody (MA562914) in IHC (P)
Immunohistochemical analysis of DLK-1 on formalin-fixed paraffin-embedded human pancreas tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissue was blocked in 1% BSA for 20 minutes at room temperature, then probed with DLK1 Recombinant Rabbit Monoclonal Antibody (PSH04-76) (Product # MA562914) at 1:200 dilution for 1 hour at room t... View More
Product Details
MA562914
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH04-76
Immunogen
Recombinant protein within human DLK-1 aa 1-327/383.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: MCF7 cell lysate, HepG2 cell lysate, SH-SY5Y cell lysate, mouse placenta tissue lysate, rat embryo tissue lysate, human pancreas tissue, mouse brain tissue, rat brain tissue.
Tissue Specificity: Group enriched (adrenal gland, pituitary gland, placenta).
Subcellular Location: Membrane, Cytoplasm.
Sequence Similarities: 83% Mouse/Rat.
Predicted band size: 41 kDa
Target Information
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenoma-associated variant of dlk1 protein; Adipocyte differentiation inhibitor protein; alternatively spliced; lacking 219 bp between positions 858 and 859; The 219 bp deletion has been demonstrated to originate by alternative splicing within an exon.; delta-like 1 homolog; dlk; DLK-1; EGF like function; fetal antigen 1; pG2; Preadipocyte factor 1; preadipocyte factor-1; PREF; Pref-1; Protein delta homolog 1; secredeltin; stromal cell derived protein 1; unnamed protein product
Gene Aliases: AW742678; Delta1; DLK; DLK-1; DLK1; DlkI; FA1; Ly107; Peg9; pG2; Pref-1; PREF1; Scp-1; SCP1; ZOG
UniProt ID: (Human) P80370, (Mouse) Q09163, (Rat) O70534
Entrez Gene ID: (Human) 8788, (Mouse) 13386, (Rat) 114587
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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