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Invitrogen
NR1D2 Recombinant Rabbit Monoclonal Antibody (0Z4F1)
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FIGURE: 1 / 1
NR1D2 Antibody (MA568713) in WB
Western blot analysis of NR1D2 in various lysates. Samples were incubated with NR1D2 Recombinant monoclonal antibody (Product # MA5-51339) using a dilution of 1:2,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA568713
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
0Z4F1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human Rev-erb beta/NR1D2 (NP_005117.3).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.54 mg/mL
Amount
10.8 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: ALPAQEQLRP KPQLEQENIK SSSPPSSDFA KEEVIGMVTR AHKDTFMYNQ EQQENSAESM QPQRGERIPK NMEQYNLNHD H
Target Information
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAR4; HZF2; orphan nuclear receptor HZF-2; orphan nuclear receptor RVR; orphan receptor; Rev-erb beta; rev-erb-beta; Rev-erb-Beta2; Rev-erba beta; Rev-ErbA-beta; Rev-erbabeta; unnamed protein product
Gene Aliases: HZF-2; Rev-erb; RVR
UniProt ID: (Mouse) Q60674, (Rat) Q63504
Entrez Gene ID: (Mouse) 353187, (Rat) 259241
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
circadian rhythm
hormone-mediated signaling pathway
regulation of lipid metabolic process
cell differentiation
intracellular receptor signaling pathway
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
circadian behavior
multicellular organismal homeostasis
regulation of inflammatory response
negative regulation of inflammatory response
lipid homeostasis
energy homeostasis
regulation of skeletal muscle cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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