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NeoBiotechnologies
Actin, Muscle Specific (Muscle Cell Marker) Recombinant Mouse Monoclonal Antibody (rMSA/953)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MSM4-2064-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rMSA/953
Immunogen
Recombinant protein corresponding to human muscle actin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACTA1; ACTA2; ACTC; ACTG2; actin alpha 1; actin, alpha 2, smooth muscle, aorta; Actin, alpha skeletal muscle; actin, alpha, cardiac 1; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; actin-like protein; alpha-actin; alpha-actin cardiac; Alpha-actin-1; alpha-actin-2; alpha-actin-3; alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; cell growth-inhibiting gene 46 protein; cytoplasmic beta-actin; cytoskeletal gamma-actin; epididymis luminal protein 176; gamma-2-actin; gamma-actin; gamma-enteric smooth muscle actin; GIG46; nemaline myopathy type 3; RP5-1068B5.2; smooth muscle alpha-actin; smooth muscle gamma-actin; unnamed protein product
Gene Aliases: ACT; ACTA; ACTA3; ACTC; ACTE; ACTG; ACTGE; ACTL3; ACTSA; ACTSG; ASD5; ASMA; CFTD; CFTD1; CFTDM; CMD1R; CMH11; CMYO2A; CMYO2B; CMYO2C; CMYP2A; CMYP2B; CMYP2C; DFNA20; DFNA26; HEL-176; LVNC4; MMIHS5; MPFD; NEM1; NEM2; NEM3; SHPM; SMDYS; SMGA; VSCM; VSCM1
structural constituent of cytoskeleton
protein binding
ATP binding
ATPase activity
myosin binding
ADP binding
protein kinase binding
microfilament motor activity
profilin binding
ubiquitin protein ligase binding
identical protein binding
structural constituent of postsynaptic actin cytoskeleton
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
muscle contraction
positive regulation of gene expression
skeletal muscle thin filament assembly
skeletal muscle fiber development
mesenchyme migration
cytoskeleton organization
response to virus
positive regulation of hepatic stellate cell migration
positive regulation of hepatic stellate cell contraction
positive regulation of ERK1 and ERK2 cascade
cellular response to transforming growth factor beta stimulus
juxtaglomerular apparatus development
glomerular mesangial cell development
positive regulation of hepatic stellate cell activation
actin filament organization
actin filament-based movement
actomyosin structure organization
actin-myosin filament sliding
cardiac myofibril assembly
cardiac muscle tissue morphogenesis
heart contraction
angiogenesis
morphogenesis of a polarized epithelium
axonogenesis
positive regulation of cell migration
maintenance of blood-brain barrier
cell motility
regulation of stress fiber assembly
regulation of focal adhesion assembly
platelet aggregation
positive regulation of wound healing
postsynaptic actin cytoskeleton organization
tight junction assembly
regulation of transepithelial transport
regulation of synaptic vesicle endocytosis
protein localization to bicellular tight junction
response to ethanol
cellular response to interleukin-6
cellular response to acetaldehyde
response to mechanical stimulus
cellular response to potassium ion
skeletal muscle fiber adaptation
response to steroid hormone
regulation of blood pressure
vascular smooth muscle contraction
response to xenobiotic stimulus
negative regulation of apoptotic process
cardiac muscle contraction
cytoplasmic actin-based contraction involved in cell motility
sarcomere organization
response to calcium ion
cellular response to interferon-gamma
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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