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LYN B Recombinant Human Protein

Catalog number:  P2907

Related applications:

Protein Assays and Analysis

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Description

LYN is a SRC family kinase expressed predominantly in hematopoietic cells. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYNB and the slightly shorter LYNA are the two isoforms of LYN.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: AAH59394
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Tag Position: C-Terminal
Target Entry: LYNB
Target Gene: v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Full Length, Recombinant, Cytoplasmic
Protein Subtype: Cytoplasmic Tyrosine Kinases
Research Category: Oncology, Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 4067
Molecular Weight: 57.4 kDa
Gene Alias: Lyn B
KinaseFamily: SRC Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 100 mM NaCl, 0.05 mM EDTA, 0.05% NP-40, 1 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.