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CSK Recombinant Human Protein

Catalog number:  P2927

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

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Description

CSK is a tyrosine kinase that has been shown to downregulate the activity of SRC oncoprotein through phosphorylation of its carboxy terminus. Since cell transformation by SRC is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004374
Assay Entry: Biochemical binding/kinetic, Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group: Tyrosine Kinases
Protein Form: Full Length, Recombinant, Cytoplasmic
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™
Target Entry: CSK
Target Gene: c-src tyrosine kinase
Gene ID (Entrez): 1445
Molecular Weight: 51.9 kDa
Protein Subtype: Cytoplasmic Tyrosine Kinases
Gene Alias: CSK
Validated Application: Kinase Assay
Protein Family: Kinases & Inhibitors
Expression System: E. coli
KinaseFamily: CSK Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 100 mM NaCl, 10% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.