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Invitrogen
PPP4C Polyclonal Antibody
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Product Details
PA1-12402
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; P PPX; pp4; PP4C; PPX; protein phosphatase 4 (formerly X), catalytic subunit; protein phosphatase X; protein phosphatase X, catalytic subunit; unnamed protein product
Gene Aliases: 1110002D08Rik; PP-X; PP4; PP4C; PPH3; PPP4; PPX
UniProt ID: (Bovine) A6H772, (Human) P60510, (Mouse) P97470, (Rat) Q5BJ92
Entrez Gene ID: (Bovine) 540398, (Human) 5531, (Mouse) 56420, (Rat) 171366
protein phosphorylation
protein dephosphorylation
regulation of double-strand break repair via homologous recombination
double-strand break repair via homologous recombination
regulation of double-strand break repair
negative regulation of protein phosphorylation
dephosphorylation
cellular response to interleukin-1
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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