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Invitrogen
ApoA1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-22558
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Apolipoprotein A1 from human plasma.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
BBS, pH 8, with 5mM EDTA, 0.075M NaCl
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody does not detect apolipoprotein A2, B, C1, C2, C3, E, or J.
Target Information
Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo a; apo A-1; APO A1; APO I; apo-AI; ApoAI; Apolipoprotein; Apolipoprotein AI; epididymis secretory sperm binding protein; MGC102525; MGC117399; MGC124929; proapo-A-I protein; proapolipoprotein; Udpgt; Ugt1; Ugt1a7; unnamed protein product
Gene Aliases: AMYLD3; apo(a); HPALP2
UniProt ID: (Human) P02647
Entrez Gene ID: (Human) 335
beta-amyloid binding
receptor binding
lipid transporter activity
protein binding
phospholipid binding
high-density lipoprotein particle binding
lipid binding
cholesterol binding
enzyme binding
heat shock protein binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
protein homodimerization activity
chemorepellent activity
receptor agonist activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
lipoprotein particle binding
intermembrane cholesterol transfer activity
negative regulation of cytokine production involved in immune response
phosphatidylcholine biosynthetic process
lipid transport
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
cholesterol metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol efflux
negative regulation of very-low-density lipoprotein particle remodeling
protein oxidation
peptidyl-methionine modification
cholesterol transport
regulation of Cdc42 protein signal transduction
negative regulation of interleukin-1 beta production
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
beta-amyloid formation
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
negative regulation of inflammatory response
positive regulation of phagocytosis
protein stabilization
negative chemotaxis
vitamin transport
positive regulation of stress fiber assembly
acylglycerol homeostasis
phospholipid homeostasis
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
ERK1 and ERK2 cascade
cholesterol import
cellular response to lipoprotein particle stimulus
positive regulation of cholesterol metabolic process
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of phospholipid efflux
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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