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Invitrogen
Penicillinase Polyclonal Antibody, Biotin
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Product Details
PA1-27255
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Penicillinase purified from Enterobacter cloacae.
Conjugate
Biotin
Biotin
Biotin
Form
Liquid
Concentration
10 mg/mL
Amount
1 mg
Purification
IgG fraction
Storage buffer
PBS, pH 7.2, with 1% BSA
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-27255 detects Penicillinase from Enterobacter cloacae samples.
Target Information
Penicillinase, also known as beta-lactamase, is an enzyme produced by certain bacteria that confers resistance to penicillin and other beta-lactam antibiotics. This enzyme works by hydrolyzing the beta-lactam ring of penicillin, rendering the antibiotic ineffective in inhibiting bacterial cell wall synthesis. Penicillinase is encoded by various bacterial genes, commonly found in plasmids or chromosomes, which can be transferred between bacteria, leading to the spread of antibiotic resistance. This enzyme is a significant concern in treating bacterial infections, as it diminishes the efficacy of beta-lactam antibiotics, which are widely used in clinical settings. The presence of penicillinase-producing bacteria necessitates the use of alternative antibiotics or combination therapies that include beta-lactamase inhibitors, such as clavulanic acid, to restore the antibiotic's effectiveness. Monitoring and studying penicillinase activity are crucial for managing antibiotic resistance and developing new therapeutic strategies to combat resistant bacterial strains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta lactamase; Oxacillinase
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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