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Invitrogen
Phospho-KV3.1 (Ser503) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-KV3.1 (Ser503) Antibody (PA1-4638) in ICC/IF
Immunocytochemistry analysis of KV3.1 (KCNC1) in Chinese Hamster Overy (CHO) cells, stably transfected with Phospho-KV3.1, (Ser503) polyclonal antibody (Product # PA1-4638) using a dilution of 1:400 (green). The image on the right shows cells that have been treated with the protein kinase C activator PMA (500 nM) while the control cells are on the left.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-4638
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser503 of rat KCNC1 conjugated to KLH
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is specific for the ~100 kDa Voltage Gated Potassium Channel KV3 1-subunit protein phosphorylated at Ser503 in Western blots of rat brain extracts.
Target Information
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ41162; FLJ42249; FLJ43491; Krc2 1; MGC129855; NGK2; Potassium channel gene 1 (alternative splicing product described in Luneau et al 1991); potassium channel, voltage gated Shaw-related subfamily C, member 1; potassium voltage gated channel, Shaw-related subfamily, member 1; Potassium voltage-gated channel subfamily C member 1; potassium voltage-gated channel, Shaw-related subfamily, member 1; RAW2; unnamed protein product; voltage-gated potassium channel subunit Kv3.1; voltage-gated potassium channel subunit Kv4
Gene Aliases: C230009H10Rik; I79_017349; Kcr2-1; KShIIIB; Kv3.1; KV4; NGK2; NGK2-KV4; Shaw
UniProt ID: (Rat) P25122, (Mouse) P15388
Entrez Gene ID: (Chinese hamster) 100763523, (Rat) 25327, (Mouse) 16502
action potential
ion transport
potassium ion transport
response to toxic substance
response to light intensity
response to auditory stimulus
response to amine
cerebellum development
optic nerve development
globus pallidus development
corpus callosum development
forebrain development
regulation of ion transmembrane transport
positive regulation of ion transmembrane transport
response to potassium ion
protein homooligomerization
protein tetramerization
transmembrane transport
cellular response to xenobiotic stimulus
response to fibroblast growth factor
potassium ion transmembrane transport
regulation of presynaptic membrane potential
regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
positive regulation of voltage-gated potassium channel activity
response to nerve growth factor
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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