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Invitrogen
UBC9 Polyclonal Antibody
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Product Details
PA1-9111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the N terminus amino acids SGIALSRLAQERK (aa 2-14).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000198131; p18; RAD6 homolog; May be involved in ubiquitin conjugation; Interacts with RAD52 and RAD51 proteins; Method: conceptual translation supplied by author.; RING-type E3 SUMO transferase UBC9; SUMO-1-protein ligase; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; ubiquitin conjugating enzyme 9; ubiquitin conjugating enzyme E2I; Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9); Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); Ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; Ubiquitin-protein ligase I; unnamed protein product
Gene Aliases: C358B7.1; P18; UBC9; UbcE2A; UBCE9; UBE2I
UniProt ID: (Human) P63279, (Rat) P63281
Entrez Gene ID: (Human) 7329, (Rat) 25573
nucleotide binding
transcription cofactor binding
RNA binding
protein binding
ATP binding
transcription factor binding
transferase activity
SUMO transferase activity
enzyme binding
HLH domain binding
small protein activating enzyme binding
SUMO conjugating enzyme activity
RING-like zinc finger domain binding
ubiquitin-protein transferase activity
protein C-terminus binding
ligase activity
ubiquitin protein ligase binding
bHLH transcription factor binding
poly(A) RNA binding
ubiquitin protein ligase activity
negative regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
regulation of receptor activity
protein ubiquitination
protein sumoylation
positive regulation of intracellular steroid hormone receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
cell division
positive regulation of SUMO transferase activity
mitotic nuclear envelope reassembly
positive regulation of cell migration
protein modification process
modulation of synaptic transmission
nuclear export
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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