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Invitrogen
SSTR2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA3-109
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues E(355) T Q R T L L N G D L Q T S I(369) of human SSTR2A.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-109 detects Somatostatin Receptor 2A in human and rat samples.
PA3-109 has been used successfully in Western blot, immunocytochemistry, and immunohistochemistry procedures. In Western blot analysis of SSTR2A transfected HEK-293 cells this antibody detects a ~62-72 kDa protein representing SSTR2A.
The PA3-109 immunogen is a synthetic peptide corresponding to residues E(355) T Q R T L L N G D L Q T S I(369) of human SSTR2A.
Target Information
SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in the cerebrum and kidney. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The receptor is coupled via pertussis toxin sensitive G proteins to inhibit adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: somatostatin receptor; somatostatin receptor 2a; somatostatin receptor subtype 2; somatotropin release-inhibiting factor receptor; SRIF-1; SS-2-R; SS2-R; SS2R; SSR2; SSTR2A; unnamed protein product
Gene Aliases: Smstr2; SST2
UniProt ID: (Human) P30874, (Rat) P30680
Entrez Gene ID: (Human) 6752, (Rat) 54305
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
spermatogenesis
cerebellum development
peristalsis
forebrain development
somatostatin signaling pathway
response to starvation
negative regulation of growth hormone secretion
cellular response to glucocorticoid stimulus
cellular response to estradiol stimulus
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
negative regulation of cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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