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Invitrogen
Galectin 1 Polyclonal Antibody
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Product Details
PA5-110617
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Galectin 1. Recombinant protein control fragment (Product #RP-91402).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EVAPDAKSFV LNLGKDSNNL CLHFNPRFNA HGDANTIVCN SKDGGAWGTE QREAVFPFQP GSVAEVCITF DQANLTVKLP DGYEFKFPNR LNLEAINYMA ADGDFKIKCV
Highest antigen sequence indentity to the following orthologs: Mouse - 87%, Rat - 90%.
Target Information
Galectin-1 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-1can be either monomeric or homodimeric and is found in a wide variety of cells and tissue types. Galectin-1 can control cell growth, proliferation, induce apoptosis of activated T cells while it can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14 kDa laminin-binding protein; 14 kDa lectin; beta-galactoside binding protein; Beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; Gal-1; Galaptin; Galectin-1; Galectin1; H-Galectin-1; HBL; HLBP14; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin, galactose binding, soluble 1; lectin, galactoside binding soluble 1; lectin, galactoside-binding, soluble, 1; pm12; Putative MAPK-activating protein PM12; RL 14.5; S-Lac lectin 1
Gene Aliases: AA410090; Gal-1; GAL1; Galbp; galectin-1; GBP; L-14.5; L14; Lect14; LGALS1
UniProt ID: (Human) B2R5E8, (Mouse) P16045, (Rat) P11762
Entrez Gene ID: (Human) 3956, (Mouse) 16852, (Rat) 56646
plasma cell differentiation
apoptotic process
signal transduction
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
T cell costimulation
multicellular organismal response to stress
positive regulation of erythrocyte aggregation
response to drug
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
myoblast differentiation
positive regulation of viral entry into host cell
response to axon injury
cellular response to glucose stimulus
cellular response to organic cyclic compound
positive regulation of dendritic cell differentiation
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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