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Invitrogen
SEMA5A Polyclonal Antibody
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Product Details
PA5-110683
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human SEMA5A. Recombinant protein control fragment (Product #RP-100996).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PWTKCSATCG GGHYMRTRSC SNPAPAYGGD ICLGLHTEEA LCNTQPCPES WSEWSDWSEC EASGVQVRAR QCILLFPMGS QCSGNTTESR PCVFDSNFIP EVSVARSSSV EEKRCGE
Highest antigen sequence indentity to the following orthologs: Rat - 91%, Mouse - 94%.
Target Information
Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996 [PubMed 8817451]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; Sema F; semaphorin F; Semaphorin-5A; Semaphorin-F
Gene Aliases: SEMA5A; SEMAF; semF
UniProt ID: (Human) Q13591
Entrez Gene ID: (Human) 9037
neural crest cell migration
positive regulation of endothelial cell proliferation
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
cell adhesion
negative regulation of cell adhesion
cell-cell signaling
nervous system development
axonal fasciculation
diencephalon development
positive regulation of cell migration
positive regulation of actin filament depolymerization
positive regulation of catenin import into nucleus
positive regulation of angiogenesis
positive regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
positive chemotaxis
negative chemotaxis
positive regulation of protein kinase B signaling
cell chemotaxis
semaphorin-plexin signaling pathway
signal clustering
negative regulation of endothelial cell apoptotic process
positive regulation of endothelial cell chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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