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Invitrogen
Renin Polyclonal Antibody
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Product Details
PA5-110692
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Renin. Recombinant protein control fragment (Product #RP-101634).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FHYINLIKTG VWQIQMKGVS VGSSTLLCED GCLALVDTGA SYISGSTSSI EKLMEALGAK KRLFDYVVKC NEGPTLPDIS FHLGGKEYTL TSADYVFQES YSSKKLCTLA IHAMDIPPPT GPTWALGATF IRKFYTEFD
Highest antigen sequence indentity to the following orthologs: Mouse - 69%, Rat - 64%.
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; aspartyl-protease; EC 3.4.23; EC 3.4.23.15; FLJ10761; REN; Renin; renin precursor, renal; unnamed protein product
Gene Aliases: ADTKD4; HNFJ2; REN; RTD
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972
kidney development
mesonephros development
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
regulation of blood vessel size by renin-angiotensin
proteolysis
regulation of blood pressure
male gonad development
response to xenobiotic stimulus
hormone-mediated signaling pathway
gene expression
response to lipopolysaccharide
response to immobilization stress
angiotensin-activated signaling pathway
drinking behavior
regulation of MAPK cascade
cell maturation
beta-amyloid metabolic process
response to cAMP
response to cGMP
cellular response to xenobiotic stimulus
juxtaglomerular apparatus development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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