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Invitrogen
TEC Polyclonal Antibody
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Product Details
PA5-110697
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human TEC. Recombinant protein control fragment (Product #RP-95919).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SNYVTGKKSN NLDQYEWYCR NMNRSKAEQL LRSEDKEGGF MVRDSSQPGL YTVSLYTKFG GEGSSGFRHY HIKETTTSPK KYYLAEKHAF GSIPEIIEYH KHNAAGLVTR LRYPVSVKGK NAPTTAGFSY EKWEINPSEL TFMRELGSGL
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC126760; MGC126762; Tyrosine-protein kinase Tec
Gene Aliases: PSCTK4; TEC
UniProt ID: (Human) P42680
Entrez Gene ID: (Human) 7006
adaptive immune response
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
regulation of platelet activation
peptidyl-tyrosine phosphorylation
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
regulation of cell proliferation
tissue regeneration
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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