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Invitrogen
Dopamine Transporter Polyclonal Antibody
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Product Details
PA5-110777
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Dopamine Transporter. Recombinant protein control fragment (Product #RP-108307).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SKCSVGLMSS VVAPAKEPNA VGPKEVELIL VKEQNGVQLT SSTLTNPRQS PVEAQDRET
Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 86%.
Target Information
The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DA transporter; dopamine transporter 1; Sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Solute carrier family 6 member 3
Gene Aliases: DAT; DAT1; PKDYS; SLC6A3
UniProt ID: (Human) Q01959
Entrez Gene ID: (Human) 6531
protease binding
receptor binding
dopamine transmembrane transporter activity
dopamine:sodium symporter activity
protein binding
drug binding
monoamine transmembrane transporter activity
protein complex binding
dopamine binding
metal ion binding
protein N-terminus binding
protein phosphatase 2A binding
primary active transporter
aging
lactation
sensory perception of smell
locomotory behavior
response to iron ion
monoamine transport
dopamine transport
adenohypophysis development
response to nicotine
positive regulation of multicellular organism growth
regulation of dopamine metabolic process
neurotransmitter biosynthetic process
response to cocaine
dopamine biosynthetic process
dopamine catabolic process
response to drug
response to ethanol
dopamine uptake involved in synaptic transmission
response to cAMP
prepulse inhibition
ammonium transmembrane transport
dopamine uptake
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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