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Invitrogen
SLC39A5 Polyclonal Antibody
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Product Details
PA5-110838
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human SLC39A5. Recombinant protein control fragment (Product #RP-91280).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ENGTLTAGGL ARLLHSLGLG RVQGLRLGQH GPLTGRAASP AADNSTHRPQ NPELSVDVWA GMPLGPSGWG DLEESKAPHL PRGPAPSGLD LLHRLLLLDH SLADHLNEDC LNGSQLLVNF GLSPAAPLTP R
Highest antigen sequence indentity to the following orthologs: Mouse - 84%, Rat - 82%.
Target Information
The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC34778; solute carrier family 39 (metal ion transporter), member 5; solute carrier family 39 (zinc transporter), member 5; Solute carrier family 39 member 5; unnamed protein product; zinc transporter 5; Zinc transporter ZIP5; ZIP-5; Zrt- and Irt-like protein 5; ZRT/IRT-like protein 5
Gene Aliases: LZT-Hs7; MYP24; SLC39A5; ZIP5
UniProt ID: (Human) Q6ZMH5
Entrez Gene ID: (Human) 283375
eye development
ion transport
zinc II ion transport
bicarbonate transport
metal ion transport
cellular cation homeostasis
BMP signaling pathway
cellular response to zinc ion starvation
positive regulation of mRNA splicing, via spliceosome
transmembrane transport
neural precursor cell proliferation
G1 to G0 transition involved in cell differentiation
zinc II ion transmembrane transport
zinc II ion transmembrane import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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