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Invitrogen
Cytokeratin 14 Polyclonal Antibody
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FIGURE: 1 / 4
Cytokeratin 14 Antibody (PA5-110884) in IHC (P)
Immunohistochemical analysis of Cytokeratin 14 in human skin and duodenum tissues using Cytokeratin 14 Polyclonal Antibody (Product # PA5-110884) using Anti-KRT14 antibody. Corresponding KRT14 RNA-seq data are presented for the same tissues.
Product Details
PA5-110884
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Cytokeratin 14. Recombinant protein control fragment (Product #RP-93527).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TYRRLLEGED AHLSSSQFSS GSQSSRDVTS SSRQIRTKVM DVHDGKVVST HEQVLRTKN
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 88%.
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-14; cytokeratin 14; Cytokeratin-14; K14; keratin 14, type I; Keratin, type I cytoskeletal 14; Keratin-14; Koebner
Gene Aliases: CK14; EBS1; EBS1A; EBS1B; EBS1C; EBS1D; EBS3; EBS4; K14; KRT14; NFJ
UniProt ID: (Human) P02533
Entrez Gene ID: (Human) 3861
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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