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Invitrogen
DDX6 Polyclonal Antibody
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Product Details
PA5-110921
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human DDX6. Recombinant protein control fragment (Product #RP-92558).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EESIPIALSG RDILARAKNG TGKSGAYLIP LLERLDLKKD NIQAMVIVPT RELALQVSQI CIQVSKHMGG AKVMATTGGT NLRDDIMRLD DTVHVVIATP GRILDLIKKG VAKVDHVQMI VLDEADKLLS QD
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD box-6; DEAD-box protein 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); Oncogene RCK; Probable ATP-dependent RNA helicase DDX6
Gene Aliases: DDX6; HLR2; P54; RCK
UniProt ID: (Human) P26196
Entrez Gene ID: (Human) 1656
regulation of translation
RNA secondary structure unwinding
viral RNA genome packaging
stem cell population maintenance
cytoplasmic mRNA processing body assembly
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
negative regulation of neuron differentiation
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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