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Invitrogen
14-3-3 gamma Polyclonal Antibody
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Product Details
PA5-110927
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human 14-3-3 gamma. Recombinant protein control fragment (Product #RP-89531).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EAVCQDVLSL LDNYLIKNCS ETQYESKVFY LKMKGDYYRY LAEVATGEKR ATVVESSEKA YSEAHEIS
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
14-3-3 gamma encodes a product that belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 protein gamma; KCIP-1; Protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; signal transduction phosphoprotein; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; unnamed protein product; YWHAG
Gene Aliases: 14-3-3GAMMA; DEE56; EIEE56; PPP1R170; YWHAG
UniProt ID: (Human) P61981
Entrez Gene ID: (Human) 7532
cytoplasmic translation
negative regulation of T cell mediated immune response to tumor cell
positive regulation of T cell mediated immune response to tumor cell
negative regulation of protein kinase activity
protein targeting
signal transduction
protein localization
regulation of signal transduction
positive regulation of cell-cell adhesion
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
cellular response to nutrient levels
cellular response to insulin stimulus
regulation of protein localization
cellular response to amino acid starvation
TORC1 signaling
cellular response to glucose starvation
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of neuron differentiation
negative regulation of translational initiation
positive regulation of translational initiation
regulation of synaptic plasticity
protein stabilization
negative regulation of T cell activation
positive regulation of T cell activation
protein localization to lysosome
protein K6-linked ubiquitination
negative regulation of TORC1 signaling
positive regulation of TORC1 signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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