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Invitrogen
ABCE1 Polyclonal Antibody
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Product Details
PA5-111079
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human ABCE1. Recombinant protein control fragment (Product #RP-104669).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KAAKGTVGSI LDRKDETKTQ AIVCQQLDLT HLKERNVEDL SGGELQRFAC AVVCIQKADI FMFDEPSSYL DVKQRLKAAI TIRSLINP
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 100%.
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2'-5'-oligoadenylate-binding protein; ABC 38; ABCE 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, sub-family E (OABP), member 1; HP68; HuHP68; Ribonuclease 4 inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNS4I
Gene Aliases: ABC38; ABCE1; OABP; OK/SW-cl.40; RLI; RLI1; RNASEL1; RNASELI; RNS4I
UniProt ID: (Human) P61221
Entrez Gene ID: (Human) 6059
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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