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Invitrogen
GLAST Polyclonal Antibody
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Product Details
PA5-111080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human GLAST. Recombinant protein control fragment (Product #RP-96858).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NGEEPKMGGR MERFQQGVRK RTLLAKKKVQ NITKEDVK
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 89%.
Target Information
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST-1; glutamate/aspartate transporter 1; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3; unnamed protein product
Gene Aliases: EA6; EAAT1; GLAST; GLAST1; SLC1A3
UniProt ID: (Human) P43003
Entrez Gene ID: (Human) 6507
L-glutamate transmembrane transporter activity
high-affinity glutamate transmembrane transporter activity
protein binding
acidic amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
symporter activity
glutamate:sodium symporter activity
glutamate binding
amino acid binding
metal ion binding
neurotransmitter uptake
ion transport
neurotransmitter transport
amino acid transport
cellular sodium ion homeostasis
chemical synaptic transmission
sensory perception of sound
response to xenobiotic stimulus
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
neutral amino acid transport
L-glutamate transport
cranial nerve development
auditory behavior
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
transepithelial transport
D-aspartate import
cellular response to cocaine
potassium ion transmembrane transport
import into cell
L-glutamate import across plasma membrane
L-aspartate import across plasma membrane
transport across blood-brain barrier
chloride transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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